The 10 Best Aesthetics Clinics in Manhattan - Updated 2025

New York City has long been a hub for beauty and aesthetics, setting trends with cutting-edge treatments and expert practitioners. As we enter 2025, the demand for personalized, advanced aesthetic services continues to rise. More than ever, people are seeking treatments that not only enhance their appearance but also support overall well-being.

To help navigate NYC’s thriving aesthetics scene, we’ve compiled a list of the top 10 clinics known for their expertise, innovation, and luxury. Whether you're looking for subtle enhancements or transformative results, these clinics are trusted destinations for safe and effective treatments.

From Dr. Syra Aesthetics & Longevity Institute, which seamlessly Botox Clinic NYC with wellness, to Bloom Time Aesthetics, a go-to for cutting-edge skincare solutions, this guide showcases the best options for achieving your beauty goals in 2025.

What are the top 10 Aesthetics Clinics in NYC?

Dr. Syra Aesthetics & Longevity Institute

Dr. Syra Hanif, the visionary behind Syra Aesthetics & Longevity Institute, is widely recognized for her expertise in aesthetic medicine and her commitment to holistic wellness. With a strong foundation in aesthetics treatment, she has earned a reputation for delivering natural-looking enhancements that prioritize both beauty and longevity. 

Her approach seamlessly blends remarkable treatments with a focus on overall well-being, making her a trusted expert in the field.

Located in the heart of Manhattan, Dr. Syra Aesthetics & Longevity Institute offers aesthetic and wellness treatments to Manhattan people. The clinic has quickly become a top destination for individuals looking to enhance their appearance while prioritizing long-term health.

From advanced skincare and anti-aging treatments to body contouring and injectables like Botox and fillers, every service is administered by highly skilled professionals. 

Dr. Syra Hanif and her team take a personalized approach to patient care, ensuring that each individual receives treatments designed to meet their unique goals. With a reputation for excellence, the institute stands as a premier name in both aesthetics and longevity.

For more information, visit Dr. Syra Aesthetics & Longevity Institute’s website.

Botox Clinic NYC

Botox Clinic NYC is a specialized clinic located at 492 6th Avenue, New York, NY 10011, in the heart of Manhattan. The clinic focuses exclusively on Botox treatments aimed at reducing fine lines and wrinkles, including areas such as crow's feet, frown lines, forehead lines, and more. ​

The clinic's team consists of board-certified providers who are experts in administering Botox injections, ensuring high-quality care tailored to each patient's aesthetic goals. They offer a 20% discount on Botox sessions, making treatments more accessible.

During the initial consultation, practitioners discuss beauty objectives, review medical history, and assess facial anatomy to create a personalized treatment plan. The actual procedure is quick, typically lasting about 10-15 minutes, with minimal downtime.

For convenience, the clinic provides detailed directions for reaching their location via public transportation, including bus and subway options from nearby PATH stations.

For more information, visit Botox Clinic NYC website

Ulthera Plus

Ulthera Plus is a rejuvenation clinic located at 30 East 60th Street, Suite 1400A, New York, NY 10022. The clinic specializes in non-invasive cosmetic treatments, including Ultherapy, Botox, dermal fillers, RF body contouring, and weight loss management.

Ultherapy is a non-surgical procedure that utilizes focused ultrasound energy to stimulate collagen production, resulting in the lifting and tightening of skin on the face, neck, and décolleté. This treatment is FDA-cleared and is known for its ability to provide a natural-looking lift without the need for surgery or downtime.

Patient experiences at Ulthera Plus vary. Some clients have reported positive outcomes, noting professional staff and satisfactory results. For instance, one client's mentioned, "Service was great and the place was really clean and super helpful." However, others have expressed dissatisfaction, citing issues such as procedural pain and prolonged waiting times. One review highlighted, I had the worst experience of my life at this place. I went in for a thread lift, and the procedure was extremely painful.

For more information, visit https://ultherapy.com/

RejuvaMed

RejuvaMed is a leading medical spa in New York City, offering non-invasive aesthetic and wellness treatments. Their expert team provides Botox, dermal fillers, microneedling, IV therapy, vitamin injections, weight loss programs, and sexual health treatments, all tailored to individual needs. With a focus on advanced techniques and patient care, they ensure natural, effective results.

Botox is one of their most sought-after services, helping reduce fine lines and wrinkles for a youthful appearance. They currently offer a 20% discount on Botox for new clients in Manhattan. In addition, their wellness treatments, including IV therapy and vitamin injections, enhance energy and overall health, making RejuvaMed a trusted destination for both beauty and well-being.

RejuvaMed uses the latest technology to deliver safe, effective treatments with minimal downtime. Whether for anti-aging, body contouring, or wellness, they provide a welcoming environment where clients can feel confident in their care.

For more information, visit https://rejuvamedny.com/

Joel Beauty

Joel Beauty is a medical spa located at 767 Lexington Ave, Suite 200, New York, NY 10065, between East 60th and 61st Streets. Specializing in non-invasive aesthetic treatments, their services include wrinkle relaxers like Botox and Dysport, lip and facial fillers, Kybella for fat reduction, microneedling, and butt enhancement procedures. The clinic emphasizes natural-looking results, tailoring each treatment to the unique features and goals of their clients.

The team at Joel Beauty comprises board-certified plastic surgeons and nurse practitioners with extensive experience in aesthetic procedures, having performed thousands of Botox and filler treatments. They are committed to enhancing clients' natural beauty without creating an overdone appearance.

For more information, visit https://www.joelbeauty.com/

Bloomtime Aesthetics

Bloomtime Aesthetics is a premier medical spa located in Manhattan's Midtown East neighborhood, dedicated to enhancing natural beauty through advanced aesthetic treatments. Their team of experienced physicians offers personalized care using state-of-the-art technology.

Bloomtime Aesthetics provides a range of services including Botox and Dysport injections to reduce fine lines and wrinkles, dermal fillers for volume restoration, Hydrafacials for skin rejuvenation, and EmSculpt NEO for muscle toning and fat reduction.

Bloomtime Aesthetics emphasizes personalized treatments tailored to individual aesthetic goals. They offer free consultations to develop customized plans for clients.

For more information, visit https://bloomtimeaesthetics.com/

Sienna Lilly Aesthetics

Sienna Lilly Aesthetics, located at 15 W 38th St Suite 709 in New York City, is dedicated to helping clients achieve Unfiltered Confidence through personalized aesthetic treatments. Founded by Sienna Salcedo, whose passion for blending beauty and science stems from her early experiences shadowing plastic surgeons, the clinic offers a range of services tailored to enhance natural beauty.

Sienna Lilly Aesthetics offerings include wrinkle reducers like Botox to smooth fine lines, dermal fillers for volume restoration, and advanced procedures such as Aquagold PRF Microneedling and PRF Undereye Treatments aimed at rejuvenating the skin. Sienna Lilly Aesthetics emphasizes individualized care, ensuring each treatment aligns with the client's unique features and goals.

For more information, visit https://www.siennalillyaesthetics.com/

Dynasty Aesthetics

Dynasty Day & Med Spa is a top-tier medical spa offering advanced aesthetic treatments for skin rejuvenation, anti-aging, body contouring, and wellness. Their expert team, led by Medical Director Barbara Franklin, NP-C, specializes in Botox, dermal fillers, laser therapy, PDO threads, acne treatments, and medical weight loss.

The spa provides personalized care using state-of-the-art technology to address concerns like wrinkles, hyperpigmentation, acne, and skin hydration. Consultations are required to create customized treatment plans, and flexible payment options are available through Cherry and Care Credit.

With a focus on safety, effectiveness, and natural-looking results, Dynasty Day & Med Spa ensures clients achieve their beauty and wellness goals.

For more information, visit https://dynastymedspa.com/

UES Aesthetics

UES Aesthetics, located at 1535 2nd Avenue in New York City, is a boutique medical aesthetics practice dedicated to enhancing natural beauty and overall wellness. Founded by board-certified family nurse practitioner Mary Youch, the clinic offers a personalized approach to aesthetic care. With over a decade of experience in immunology, IV infusions, and cosmetic injections, Mary ensures each treatment is tailored to the client’s unique goals for a refreshed and rejuvenated look.

The clinic specializes in Botox injections to smooth wrinkles and fine lines, IV NAD infusions to boost energy and metabolism, and vitamin infusions to enhance immunity and hydration. Each treatment is designed to deliver effective, natural-looking results while promoting overall well-being. 

UES Aesthetics stands out for its individualized consultations, ensuring clients receive the best recommendations based on their needs.

For more information, visit https://uesaesthetics.com/

SKINNEY Medspa

SKINNEY Medspa, founded by identical twin sisters Adriana and Marisa Martino, is a premier medical spa offering a comprehensive range of non-invasive cosmetic treatments. With locations in New York City and Miami, the spa integrates traditional spa services with advanced medical aesthetics in a soothing, relaxing environment.

The spa provides a variety of services designed to enhance natural beauty and address individual concerns. These include CoolSculpting for fat reduction, Sculpt NEO for muscle toning and fat burning, Botox to prevent and smooth wrinkles, Sofwave for skin tightening and anti-aging, and dermal fillers to plump, smooth, and contour the skin. Each treatment is tailored to deliver effective, natural-looking results with minimal to no downtime.

SKINNEY Medspa is renowned for its state-of-the-art technologies and personalized service, ensuring clients receive top-tier care in a modern, spa-like atmosphere. With over 14 years in business and more than a million treatments performed, the spa has garnered numerous five-star reviews, reflecting high client satisfaction.

For more information, visit https://skinneymedspa.com/